We have called this editorial Resilience and Global Sustainability Contributions among the set of papers raise the challenge of multiscale interactions and collaborations in this context. One of them on resilience thinking connects resilience to global sustainability by arguing that the relatively stable basin of attraction of the last 10,000 years, within which agriculture and human civilizations have largely developed and flourished, is where we would like to remain. However, it will require that societies seriously consider ways to explore options for deliberate transformation of social-ecological systems at local and regional scales and across scales that erode Earth System resilience and instead foster those that contribute to global sustainability.